Table 2

WHO classification of risk for pulmonary hypertension1

A. Drugs and toxins
1. Definite
  • Aminorex
  • Fenfluramine
  • Toxic rapeseed oil
2. Very likely
  • Amphetamines
  •l-tryptophan
3. Possible
  • Meta-amphetamines
  • Cocaine
  • Chemotherapeutic agents
4. Unlikely
  • Antidepressants
  • Oral contraceptives
  • Oestrogen therapy
  • Cigarette smoking
B. Demographic and medical conditions
1. Definite
  • Sex
2. Possible
  • Pregnancy
  • Systemic hypertension
3. Unlikely
  • Obesity
C. Diseases
1. Definite
  • HIV infection
2. Very likely
  • Portal hypertension/liver disease
  • Collagen vascular diseases
  • Congenital systemic-pulmonary cardiac shunts
3. Possible
  • Thyroid disorders