Distribution of exon 5 and exon 6 polymorphism of GSTP1 genotypes in COPD and control groups
| Number of individuals (% of group) | Odds ratio (95% CI) for homozygotes of wild type | Major allele frequency | |||||
|---|---|---|---|---|---|---|---|
| Homozygous wild type | Heterozygote | Homozygous mutant | |||||
| Exon 5 polymorphism (Ile105Val) | |||||||
| Control group | 26 (52%) | 22 (44%) | 2 (4%) | 1 | 0.74 | ||
| COPD group | 42 (79%)2-150 | 11 (21%) | 0 (0%) | 3.5 (2.7 to 4.6) | 0.90 | ||
| Exon 6 polymorphism (Ala114Val) | |||||||
| Control group | 50 (100%) | 0 (0%) | 0 (0%) | 1.00 | |||
| COPD group | 53 (100%) | 0 (0%) | 0 (0%) | 1.00 | |||
↵2-150 p = 0.009.