Subject characteristics
| COPD | Healthy | |
|---|---|---|
| Sex (M/F) | 12/4 | 12/4 |
| Smokers/ex-/never smokers | 8/8/0 | 8/6/2 |
| Age (years) | 66 (52–75) | 63 (47–73) |
| Pack-years | 35 (15–51) | 23 (0–55) |
| FEV1 (% pred) | 63 (32–77)1-150 | 113 (93–113) |
| ΔFEV1 (% pred) | 6 (−4–9) | 2 (−7–7) |
| FEV1/VC (%) | 48 (28–63)1-150 | 77 (68–91) |
| Serum eosinophils (109/ml) | 160 (44–330) | 130 (80–290) |
| PC20 methacholine (mg/ml) | 0.55 (0.04–3.45)1-150 | >8 |
| PC20AMP (mg/ml) | 16.52 (1.23–80)1-150 | >80 |
Data are presented as medians (ranges).
FEV1 = forced expiratory volume in one second; VC = vital capacity; PC20 = provocative concentration causing a 20% fall in FEV1; AMP = adenosine 5′-monophosphate. ΔFEV1 = increase in FEV1 after inhaling 1 mg of terbutaline by Turbohaler.
↵1-150 p<0.0001.