Table 1

Characteristics of study participants

Subjects	Age (yrs)	Sex	FEV₁pre-BD (% pred)	FEV₁post-BD (% pred)	Change in FEV₁ after BD (%)	PD₂₀M (mg)	ICS dosage (μg/day)	Atopy status
Asthmatic subjects not on ICS
1	23	M	97	102	5.2	0.03	N/A	+
2^1-160	48	M	72	87	20.8	0.02	N/A	+
3^1-160	41	M	110	115	4.5	0.07	N/A	+
4	32	M	114	121	6.1	0.23	N/A	+
5	44	M	58	82	41.1	0.002	N/A	+
6^1-160	22	F	99	105	6.1	0.03	N/A	+
7^1-160	35	F	73	82	12.3	0.08	N/A	−
Mean	35		89	99.1	13.8	0.033^1-150
Interquartile range	23–44		72–110	82–115	5.2–20.8	0.02–0.08

Asthmatic subjects on ICS
1	45	M	96	124	29.2	0.16	200	+
2	69	M	71	90	26.8	0.01	500	+
3	51	F	99	112	13.1	0.001	500	+
4	34	M	91	105	15.4	0.07	400	+
5^1-160	64	F	97	125	28.9	0.08	200	−
6	24	F	98	111	13.3	0.11	500	−
7	61	M	103	108	4.9	0.63	1000	+
8	50	M	90	100	11.1	0.01	1000	+
9	23	F	99	103	4	0.04	800	+
10	49	M	81	91	12.3	0.49	800	+
11	55	M	65	91	40	0.02	800	+
12^1-160	32	M	76	95	25	0.01	1000	+
13^1-160	48	M	60	81	35	0.01	1500	−
14	64	M	98	116	18.4	0.03	1000	−
15^1-160	49	F	96	111	15.6	0.03	1000	−
Mean	48		88	104.2	19.5	0.036^1-150	746.7
Interquartile range	34–61		76–98	91–112	12.3–28.9	0.01–0.16	500–1000

Non-asthmatic controls
1	37	M	95	N/D	N/D	6.4	N/A	+
2	22	F	103	N/D	N/D	Negative	N/A	+
3	44	M	80	86	N/D	Negative	N/A	+
4	24	M	117	N/D	N/D	Negative	N/A	+
5^1-160	23	M	109	114	N/D	Negative	N/A	−
6	20	M	102	N/D	N/D	Negative	N/A	−
7	21	F	125	N/D	N/D	Negative	N/A	−
8	25	M	105	100	N/D	Negative	N/A	−
9^1-160	21	F	96	101	N/D	Negative	N/A	−
10^1-160	32	M	110	116	N/D	Negative	N/A	−
11	20	M	117	N/D	N/D	Negative	N/A	−
Mean	26		105.4
Interquartile range	21–32		96–117

FEV₁ = forced expiratory volume in one second; BD = bronchodilator; PD₂₀M = dose of methacholine required to provoke a fall in FEV₁ of 20% or more; ICS = inhaled corticosteroids; N/A = not applicable; N/D = not done.
↵1-150 Geometric mean.
↵1-160 Subjects had bronchodilator before bronchoscopy.