Electrophysiological results for the study patient. Mean (SD) values for a control group and a group of patients with CF are given for comparison
| Control group | Study patient | CF group | |
|---|---|---|---|
| Nasal potential difference (mV) | n = 25 | n = 23 | |
| baseline and ΔPD after addition of: | |||
| baseline | −24 (11) | −52 | −45 (10) |
| amiloride | +10 (6) | +21 | +21 (9) |
| Cl– free solution | −15 (10) | −3 | −1 (5) |
| isoprenaline | −8 (4) | −4 | −2 (3) |
| ATP | −1 (3) | 0 | −1 (3) |
| Intestinal current measurement (μA/cm2) | n = 50 | n = 51 | |
| ΔIscafter addition of: | |||
| amiloride | −8.7 (11) | −4.9 | −8.7 (11) |
| carbachol | 38.5 (23) | 45.5 | −5.3 (10) |
| histamine (after DIDS incubation) | 33.0 (26) | 19.4 | −5.0 (10) |