Table 1

Clinical data

	Case no.
	1	2	3	4	5	6	7	8	9	10
Age at onset (years)	65	60	32	58	42	40	35	33	61	45
Sex	F	M	F	M	M	F	F	M	M	F
Smoking (pack years)	30	80	17	64	13	3	0	60	67	21
Quit at presentation	No	No	No	1 year	1 year	2 years	Non-smoker	No	No	No
Occupational exposure	No	No	No	No	No	No	Solder	No	Wood dust	No
Relevant PMH	No	No	Scleroderma	No	CREST	Scleroderma	No	No	No	No
Symptoms
SOB	Yes	No	No	Yes	No	Yes	Yes	Yes	Yes	Yes
Cough	Yes	No	No	No	No	No	No	Yes	Yes	No
Sputum	No	No	No	No	No	No	No	No	No	No
Haemoptysis	Yes	No	No	No	No	Yes	No	No	No	No
Chest pain/discomfort	No	Yes	No	No	No	No	Yes	No	No	Yes
Fever/weight loss	No	No	No	No	No	No	No	Yes	Yes	No
Basal crackles	Yes	No	No	Yes	Yes	Yes	Yes	Yes	No	No
Clubbing	Yes	No	No	No	No	No	No	No	Yes	No
Other			Screened^1-150		Screened^1-150

PMH = past medical history; SOB = shortness of breath.
↵1-150 Patients with scleroderma found to have reduced transfer factor.