Mean (SE) values for pulmonary function tests and inflammatory markers in patients with cystic fibrosis during an exacerbation and after antibiotic treatment and in controls
| Patients (n = 12) | Controls (n = 12) | ||||
|---|---|---|---|---|---|
| Exacerbation | After treatment | ||||
| FEV1 (l) | 1.6 (0.3)a1 | 1.89 (0.3)a1,a2 | 4.42 (0.3) | ||
| FVC (l) | 2.37 (0.35)a1 | 2.70 (0.40)a1,a2 | 5.16 (0.30) | ||
| CRP (g/l) | 48 (19)a1 | 22 (7)a1,a2 | 2 (0.6) | ||
| NEAPC (mg/l) | 4.6 (2.4)a1 | 1.5 (0.6)a1,a2 | 0.18 (0.02) | ||
| WCC (×109/l) | 10.8 (0.8)a1 | 9.3 (0.7)a1,a2 | 5.5 (0.2) | ||
FEV1 = forced expiratory volume in one second; FVC = forced vital capacity; CRP = C reactive protein; NEAPC = neutrophil elastase α1-antiprotease complexes; WCC = white cell count.
1-a p<0.05, 1versus control, 2versus value during exacerbation.