Table 1

Transcription factor binding to DNA during each treatment period (as % of Oct-1 binding)

Subject		GR binding			CREB binding				NFκB binding
Subject		P	T		B	BT			P	T	B	BT	P	T	B	BT
1	0.76	0.76	0.93	1.52	0.40	0.43	0.55	0.64		8.11	7.06	4.63	8.29
2	1.00	0.65	1.18	2.91	0.56	0.40	0.62	0.40		14.25	11.29	2.39	4.66
3	0.92	0.75	0.76	0.88	0.51	0.29	0.48	0.48		1.39	8.03	5.83	3.26
4	0.97	0.72	1.02	1.60	0.85	1.47	1.10	0.71		20.33	7.12	5.88	14.33
5	0.56	0.34	0.88	0.66	0.31	0.41	0.51	0.51		9.33	10.10	4.25	4.10
6	1.06	1.38	1.85	1.38	1.74	2.14	0.74	1.25		13.10	14.88	18.10	0.99
7	0.74	0.55	0.6	0.84	0.54	1.11	0.28	0.68		1.79	18.50	5.52	13.66
Mean	0.86	0.74	1.03	1.40	0.70	0.89	0.61	0.67		9.76	11.00	6.66	7.04
SD	0.16	0.30	0.38	0.70	0.45	0.65	0.24	0.26		6.32	3.99	4.81	4.84

GR = glucocorticoid receptor; CREB = cAMP response element binding protein; NFκB = nuclear factor kappa B; P = placebo; T = terbutaline; B = budesonide; BT = budesonide + terbutaline.