Table 6

Responsiveness to changes within subjects and differences in changes between salmeterol + ipratropium bromide (n = 45), salmeterol + placebo (n = 43), and placebo + placebo (n = 45)

  • SGRQ = St George‚Äôs Respiratory Questionnaire; CRQ = Chronic Respiratory Disease Questionnaire.

  • 6-151 Covariance analysis on change scores with treatment groups as a factor and baseline score as a covariate. Improvement is indicated by a minus for the SGRQ and a plus for the CRQ.

  • Within-patient changes:

  • 6-150 p<0.05;

  • 6-160 p<0.001.