Table 1

Pathophysiological mechanisms impairing function of respiratory muscles after surgery

Effect on neural control of respiratory muscles (e.g. phrenicotomy)
Effect on integrity of respiratory muscles by the surgical incision
Reflex mechanisms (phrenic nerve inhibition)
Change in the length/tension relationship (change in FRC)
Change in the thoracoabdominal mechanics (e.g. reduction of rib cage compliance)
Anaesthesia (pharmacological agents/loads) and postoperative pain
Specific surgical procedures (e.g. cooling during open heart surgery)
Surgery on organs affecting respiratory muscle function (e.g. parathyroidectomy)