Table 3

Recommended drug regimens for adults and children

Initial phaseContinuation phaseTotal months
DrugsMonthsDrugsMonths
Respiratory and non-respiratoryHRZ(E)2HR46
Meningitis/CNSHRZ(E)2HR1012
ChemoprophylaxisH66
HR33
For isoniazid resistant organismsR66
  • R = rifampicin; H = isoniazid; Z = pyrazinamide; E = ethambutol.

  • (E) Ethambutol may be omitted in previously untreated white patients who are known to be HIV negative or thought likely to be on negative risk assessment and not contacts of a case of known drug resistance.