Drug | Daily dosage | Intermittent dosage | |||||
---|---|---|---|---|---|---|---|
Children | Adults | Children | Adults | ||||
Weight | Dose | Weight | Dose | ||||
Isoniazid | 5 mg/kg2-150 | — | 300 mg | 15 mg/kg 3 times weekly | — | 15 mg/kg 3 times weekly | |
Rifampicin | 10 mg/kg | <50 kg | 450 mg | 15 mg/kg 3 times weekly | — | 600–900 mg 3 times weekly | |
⩾50 kg | 600 mg | ||||||
Pyrazinamide | 35 mg/kg | <50 kg | 1.5 g | 50 mg/kg 3 times weekly | <50 kg | 2.0 g | |
⩾50 kg | 2.0 g | ⩾50 kg | 2.5 g 3 times weekly | ||||
75 mg/kg twice weekly | <50 kg | 3.0 g | |||||
⩾50 kg | 3.5 g twice weekly | ||||||
Ethambutol2-160 | 15 mg/kg | 15 mg/kg | 30 mg/kg 3 times weekly | 30 mg/kg 3 times weekly | |||
45 mg/kg twice weekly | 45 mg/kg twice weekly |