Table 2

Primary results of the meta-analyses

Meta-analysis		No. of studies included in the analysis		Pooled sensitivity				Pooled specificity		Estimate of the likelihood ratio
Meta-analysis		No. of studies included in the analysis		Estimate (95% CI)	Homogeneity (p value)			Estimate (95% CI)	Homogeneity (p value)	Estimate of the likelihood ratio
Malignant vs all other categories	48	86.1% (83.8 to 88.4)	0.001		98.8% (98.4 to 99.2)	0.29	72^2-150
Malignant or suspicious vs all other categories	48	88.3% (86.3 to 90.3)	0.001		98.2% (97.7 to 98.7)	0.22	49^2-150
Suspicious vs all other categories (excluding “malignant”)	21	25.7% (18.4 to 33.0)	0.001		98.3% (97.5 to 99.1)	0.63	15^2-150
Benign vs all other categories	35	94.7% (93.4 to 96.0)	0.001		81.0% (74.7 to 87.3)	0.001	0.07^2-151
Benign specific vs all other categories	20	99.8% (99.6 to 100.0)	0.001		44.2% (31.2 to 57.2)	0.001	0.005^2-151

↵2-150 Positive likelihood ratio.
↵2-151 Negative likelihood ratio.