Recruitment and subject characteristics
| W/E | ISC | p value | |
|---|---|---|---|
| No. (%) of responders to study | |||
| Men | 154 (43) | 183 (67) | <0.001 |
| Women | 191 (58) | 161 (71) | <0.001 |
| No. (%) smokers and ex-smokers | |||
| Men | 77 (50) | 63 (34) | 0.298 |
| Women | 102 (53) | 8 (5) | <0.001 |
| Age (years) | |||
| Men | 34.7 (15) | 29.7 (16) | 0.002 |
| Women | 37.7 (14) | 36.0 (16) | 0.368 |
| Age onset (years) | |||
| Men | 18.4 (17) | 18.0 (15) | 0.763 |
| Women | 22.7 (17) | 23.5 (15) | 0.541 |
| Mean (SD) FEV1 (l) | |||
| Men | 2.91 (1.0) | 2.60 (0.8) | <0.001 |
| Women | 2.27 (0.8) | 1.88 (0.7) | <0.001 |
| Mean (SD) % predicted FEV1 | |||
| Men | 76.9 (22.4) | 81.9 (20.8) | 0.022 |
| Women | 81.0 (21.8) | 78.1 (21.5) | 0.146 |
| Mean (SD) peak flow (l/min) | |||
| Men | 439.3 (125.7) | 431.9 (113.1) | 0.195 |
| Women | 355.2 (100.5) | 333.2 (93.3) | <0.001 |
| Mean (SD) % predicted peak flow | |||
| Men | 85.9 (22.1) | 92.7 (21.4) | 0.006 |
| Women | 95.8 (24.7) | 93.1 (23.9) | 0.223 |
W/E = white European; ISC = Indian subcontinent; FEV1 = forced expiratory volume in one second.
Analysis adjusted for age with differences compared by Mantel-Haenszel χ2. p values of <0.05 considered significant.