Cox’s proportional hazards model for survival of patients with idiopathic pulmonary fibrosis (IPF) in the New Mexico ILD Registry
Factor | Category | RH5-150 | 95% CI | p value5-160 |
---|---|---|---|---|
Age at diagnosis | Under 65 years | 1.00 | ||
65–74 years | 2.12 | 1.13 to 3.99 | ||
75 years or older | 2.74 | 1.49 to 5.06 | 0.006 | |
Chest radiographic profusion | Mild | 1.00 | ||
Moderate | 1.29 | 0.73 to 2.28 | ||
Severe | 3.10 | 1.66 to 5.77 | 0.001 | |
FVC (% predicted) | >80 | 1.00 | ||
60–79 | 1.23 | 0.64 to 2.37 | ||
<60 | 1.82 | 0.92 to 3.58 | 0.180 | |
Duration of symptoms prior to diagnosis | <12 months | 1.00 | ||
⩾12 months | 0.52 | 0.23 to 1.20 | 0.126 | |
Sex | Women | 1.00 | ||
Men | 1.00 | 0.65 to 1.52 | 0.987 | |
Cigarette smoking | Never smoked | 1.00 | ||
Ever smoked | 0.72 | 0.45 to 1.16 | 0.177 | |
Ethnicity | Non-Hispanic White | 1.00 | ||
Hispanic | 1.32 | 0.84 to 2.08 | ||
Other | 0.95 | 0.41 to 2.12 | 0.469 | |
Corticosteroids | Not treated | 1.00 | ||
Treated | 2.07 | 1.26 to 3.37 | 0.004 | |
Diagnostic code (ICD-9) | IPF (516.3) | 1.00 | ||
Pulmonary fibrosis (515) | 1.43 | 0.91 to 2.26 | ||
Primary or interstitial pneumonitis | 0.55 | 0.25 to 1.21 | 0.060 | |
Biopsy | Transbronchial | 1.00 | ||
Open lung/autopsy | 1.79 | 0.83 to 3.83 | ||
No biopsy | 1.09 | 0.64 to 1.87 | 0.312 |