Factor | Category | No. | Five year survival (95% CI) | p value for log rank test |
---|---|---|---|---|
Age at diagnosis | Under 65 years | 47 | 68.8 (55.0 to 82.6) | |
65–74 years | 70 | 50.7 (38.4 to 63.0) | ||
75 years or older | 92 | 34.5 (23.6 to 45.3) | 0.001 | |
Chest radiographic profusion | Mild | 68 | 53.0 (39.5 to 66.4) | |
Moderate | 45 | 48.6 (33.2 to 64.0) | ||
Severe | 24 | 23.8 (6.3 to 41.3) | 0.008 | |
FVC (% predicted)4-150 | >80 | 38 | 55.6 (36.9 to 74.4) | |
60–80 | 59 | 49.1 (35.2 to 63.2) | ||
<60 | 46 | 33.7 (18.2 to 49.2) | 0.124 | |
FEV1 (% predicted) | >80 | 53 | 56.1 (41.4 to 70.8) | |
60–80 | 49 | 50.5 (35.6 to 65.4) | ||
<60 | 41 | 37.4 (20.8 to 54.1) | 0.103 | |
Airflow | Normal | 53 | 56.1 (41.4 to 70.8) | |
Obstructed | 33 | 46.1 (26.6 to 65.5) | ||
Restricted | 57 | 43.3 (29.7 to 56.9) | 0.417 | |
Duration of symptoms prior to diagnosis | <12 months | 152 | 50.0 (36.5 to 53.5) | |
⩾12 months | 21 | 70.7 (50.9 to 90.5) | 0.028 | |
Sex | Women | 94 | 47.6 (36.8 to 58.4) | |
Men | 115 | 47.5 (37.5 to 57.5) | 0.915 | |
Smoking | Never smoked | 59 | 44.1 (30.9 to 57.3) | |
Ever smoked | 128 | 50.3 (40.6 to 60.0) | 0.250 | |
Ethnic group | Hispanic | 48 | 39.9 (25.5 to 54.2) | |
Non-Hispanic White | 128 | 51.2 (41.7 to 60.8) | 0.139 | |
Corticosteroids | Not treated | 114 | 52.7 (43.0 to 62.3) | |
Treated | 76 | 41.6 (29.5 to 53.8) | 0.292 | |
Diagnostic code (ICD-9) | IPF (516.3) | 129 | 46.4 (37.0 to 55.8) | |
Pulmonary fibrosis (515) | 56 | 42.1 (28.2 to 56.0) | ||
Primary or interstitial pneumonitis | 24 | 66.7 (47.8 to 85.5) | 0.113 | |
Biopsy | Transbronchial | 68 | 52.9 (40.1 to 65.7) | |
Open lung/autopsy | 20 | 44.0 (18.0 to 70.0) | ||
No biopsy | 116 | 45.8 (36.1 to 55.5) | 0.526 |
↵4-150 Comparison between % predicted FVC <60 and % predicted FVC >60, p value = 0.044.