Table 1

Association with atopy for prenatal and perinatal risk factors, immunisations, and childhood infections

		% atopic (n) if risk factor		Atopy		Unadjusted odds ratios (95% CI)
		Absent	Present	Atopy		Asthma	Hay fever	Eczema
Prenatal and perinatal factors
Maternal atopy	42 (1564)	59 (369)	1.92 (1.52 to 2.41)^***	1.94 (1.52 to 2.48)^***	1.91 (1.50 to 2.44)^***	1.73 (1.33 to 2.26)^***
Maternal smoking	45 (1440)	48 (493)	1.16 (0.95 to 1.43)	1.29 (1.03 to 1.63)^1-150	1.04 (0.82 to 1.32)	0.97 (0.75 to 1.26)
Low birth weight	45 (1388)	51 (82)	1.26 (0.81 to 1.96)	1.00 (0.60 to 1.66)	0.92 (0.55 to 1.55)	1.11 (0.64 to 1.94)
Bottle feeding	45 (947)	47 (506)	1.07 (0.86 to 1.33)	1.09 (0.86 to 1.40)	1.08 (0.85 to 1.39)	1.02 (0.77 to 1.35)
Immunisations
Pertussis	36 (498)	46 (1357)	1.57 (1.28 to 1.95)^***	1.44 (1.17 to 1.85)^**	1.56 (1.21 to 2.02)^**	1.37 (1.12 to 2.01)^1-150
Measles	40 (196)	44 (1659)	1.16 (0.86 to 1.57)	1.13 (0.79 to 1.61)	1.23 (0.86 to 1.77)	1.12 (0.74 to 1.68)
Specific infections
Whooping cough	43 (1754)	56 (101)	1.73 (1.16 to 2.59)^1-150	1.83 (1.21 to 2.79)^**	1.19 (0.76 to 1.87)	1.51 (0.94 to 2.44)
Measles	44 (1770)	40 (85)	0.86 (0.55 to 1.33)	0.91 (0.55 to 1.53)	0.93 (0.55 to 1.56)	0.82 (0.44 to 1.51)
Mumps	41 (1492)	54 (363)	1.69 (1.34 to 2.13)^***	1.41 (1.10 to 1.83)^1-150	1.85 (1.44 to 2.39)^***	1.43 (1.07 to 1.91)^1-150
Croup	43 (1723)	57 (132)	1.78 (1.24 to 2.54)^**	1.60 (1.09 to 2.33)^1-150	1.69 (1.16 to 2.46)^1-150	1.75 (1.16 to 2.64)^1-150
Chickenpox	41 (1270)	49 (585)	1.41 (1.16 to 1.72)^**	1.44 (1.15 to 1.80)^**	1.33 (1.06 to 1.66)^1-150	1.40 (1.09 to 1.81)^1-150
Antibiotics < 2 years	28 (618)	51 (1237)	2.62 (2.13 to 3.23)^***	3.19 (2.43 to 4.18)^***	2.04 (1.59 to 2.62)^***	2.04 (1.53 to 2.73)^***

↵1-150 p<0.05; ^**p<0.005; ^***p<0.0005.