Table 4

Accuracy of clinical criteria and non-invasive and invasive diagnostic techniques for ventilator associated pneumonia stratified according to whether or not antibiotics were given during the last 48 hours before death

Diagnostic methodWithout antibiotics (n = 8)With antibiotics (n = 17)
Sensitivity
% (n)
Specificity
% (n)
Sensitivity
% (n)
Specificity
% (n)
Clinical4-150 67 (4/6)0  (0/2)71  (5/7)90  (9/10)
TBA83 (5/6)100 (2/2)57 (4/7)90 (9/10)
Protected BAL17 (1/6)100 (2/2)57 (4/7)100 (10/10)
BAL67 (4/6)50 (1/2)86 (6/7)60 (6/10)
PSB83 (5/6)100 (2/2)43 (3/7)70 (7/10)
Any invasive83 (5/6)50 (1/2)86 (6/7)50 (5/10)
Any non-invasive or invasive83 (5/6)50 (1/2)86 (6/7)50 (5/10)
  • 4-150 Chest radiograph infiltrates plus two of the following: leucocytosis, purulent secretions, fever.

  • TBA = tracheobronchial aspirates; BAL = bronchoalveolar lavage; PSB = protected specimen brush.