Investigation profiles at presentation and re-assessment
| Patient no. | |||||||
|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | |
| Blood leucocyte count (×109/ml) | 11.7 (11.8) | 7.6 (6.5) | 8.3 (7.2) | 9.6 (7.0) | 13.9 (9.1) | 6.1 (6.4) | 9.0 (5.8) |
| Erythrocyte sedimentation rate (mm/h) | 12 (20) | 37 (2) | 63 (54) | 86 (3) | 45 (32) | 48 (6) | 26 (39) |
| C reactive protein (<1 mg/dl) | <0.3 (<0.3) | <0.3 (<0.3) | 1.0 (<0.3) | 6.4 (<0.3) | 0.6 (<0.3) | <0.3 (<0.3) | <0.3 (<0.3) |
| Auto-antibodies | Negative | Negative | Negative | Negative | Negative | Negative | Negative |
| Complement 3 and 4 | Normal | Normal | Normal | Normal | Normal | Normal | Normal |
| 24 hour sputum production (ml/24 h) | 60 (20) | 30 (0) | 10 (0) | 20 (0) | 30 (20) | 20 (5) | 100 (50) |
| FEV1 (% predicted) | 23 (47) | 84 (142) | 41 (64) | 57 (98) | 22 (25) | 53 (54) | 44 (86) |
| FVC (% predicted) | 61 (92) | 95 (143) | 52 (83) | 67 (114) | 35 (42) | 45 (109) | 101 (87) |
| FEV1/FVC | 29 (39) | 74 (83) | 69 (77) | 63 (63) | 47 (60) | 80 (44) | 38 (71) |
| RV (% predicted) | 212 (180) | 147 (116) | 167 (131) | 270 (164) | 101 (90) | 144 (156) | 164 (185) |
| VC (% predicted) | 64 (76) | 93 (140) | 66 (110) | 70 (119) | 37 (55) | 39 (97) | 96 (70) |
| RV/TLC | 58 (48) | 38 (24) | 57 (36) | 64 (37) | 57 (55) | 62 (42) | 56 (55) |
| Kco (% predicted) | 84 (101) | 101 (82) | 105 (106) | 111 (90) | 101 (100) | 98 (138) | 140 (138) |
| Pao 2 (kPa)3-150 | 8.3 (10.2) | 12 (11.4) | 9.3 (10.3) | 8.2 (10.5) | 8.0 (9.8) | 8.1 (10.0) | 9.0 (11.0) |
Data shown are measurements made at presentation and re-assessment (in parentheses).
↵3-150 Normal range for arterial blood gases when breathing room air 10.6–14 kPa.
FEV1=forced expiratory volume in one second; FVC=forced vital capacity; RV=residual volume; VC=vital capacity; TLC=total lung capacity; Kco=carbon monoxide transfer coefficient; Pao 2=arterial oxygen tension.