Table 4

Relation of slope to total IgE and positive skin prick tests, adjusted for each other and centre, sex, baseline lung function, height, parental atopy, number of siblings, season of testing, and age/smoking interaction

	Mean difference from negative test or regression coefficient	95% confidence interval	p value
Total IgE (log₁₀kU/l)	−0.31	−0.52 to −0.11	0.003
Positive skin prick test to:
D pteronyssinus	−0.77	−1.09 to −0.45	<0.001
Timothy grass	−0.64	−1.00 to −0.28	<0.001
Cladosporium	−0.47	−1.16 to 0.22	0.18
Birch	1.05	0.47 to 1.63	<0.001
Any of Alternaria, olive,Parietaria, common ragweed	−0.43	−0.88 to 0.03	0.07
Cat (at age 20)	−1.12	−1.94 to −0.29	0.008
Additional increase per year of age in cat sensitised subjects	0.08	0.02 to 0.14	0.008

Number of subjects=749. Total within centre variation explained 33.0%.