Table 1

Baseline clinical data of the 21 patients who completed the study

Mean (SD)Range
Age65.4 (7.4)51–77
Smoking (pack years)58.7 (28.0)20–120
FEV1 (l)1.00 (0.40)0.51–2.02
FEV1 (% predicted)36.1 (13.1)18.5–62.3
FVC (l)2.58 (0.61)1.35–3.78
FVC (% predicted)73.7 (16.2)38.3–97.6
FEV1/FVC (%)38.7 (10.8)21.2–58.7
TLC (l)6.14 (0.99)4.15–8.80
TLC (% predicted)110.2 (14.8)72.7–140.8
RV/TLC (%)51.0 (8.8)37.5–69.1
Tlco (mmol/min/kPa)5.77 (1.48)2.95–8.57
Tlco (% predicted)71.2 (18.7)33.2–107.9
Kco (mmol/min/l/kPa)1.22 (0.39)0.64–2.15
Resting Pao 2(kPa)10.0 (1.2)8.1–12.3
Resting Paco 2 (kPa)5.5 (0.5)4.3–6.7
  • FEV1 = forced expiratory volume in one second; FVC = forced vital capacity; TLC = total lung capacity; RV = residual volume; Tlco = carbon monoxide transfer factor; Kco = carbon monoxide transfer coefficient; Pao 2, Paco 2 = arterial oxygen and carbon dioxide tensions.