Table 1

MDRTB and additional drug resistances: years 2008 and 2009 (complete drug profiles)

Total MDRTB strains with complete DST profile107100%
Group 1
 MDRTB (R+H)5148%
 MDRTB (R+H)+resistance to any reserve drug*1733%
 MDRTB (R+H)+sensitivity to all reserve drugs*3467%
Group 2
 MDRTB (R+H)+/or E+/or Z5652%
 MDRTB (R+H)+/or E+/or Z+resistance to reserve any drugs*3461%
 MDRTB (R+H)+sensitivity to all reserve drugs*2239%
Resistance to first-line drugs
Resistance to reserve drugs
  • In multidrug-resistant tuberculosis (MDRTB) isolates the rate of resistance to any reserve drug was significantly greater when accompanied by resistance to another first line drug (group 2 vs group 1) (Fisher's exact test p=0.0065).

  • * Reserve drugs: amikacin, capreomycin, kanamycin, moxifloxacin, ofloxacin and prothionamide (streptomycin is not included).

  • Any of amikacin, capreomycin and kanamycin.

  • Ofloxacin and/or moxifloxacin.

  • DST, drug sensitivity test; E, ethambutol; H, isoniazid; R, rifampicin; XDR, extensively drug resistant; Z, pyrazinamide.