Clinical markers of disease severity split by GSTM1 genotype
| Normal (n=27) | Null (n=26) | Mean difference | 95% CI | p value | |
|---|---|---|---|---|---|
| Mean FEV1 (% predicted) | 86.8 | 79.8 | 7.0 | −2.9 to 16.9 | 0.16 |
| Mean weight zscore | −0.56 | −0.63 | 0.07 | −0.47 to 0.61 | 0.79 |
| Mean Chrispin-Norman chest radiographic score | 11.0 | 15.0 | 4 | −7.3 to −0.8 | 0.02 |
| Mean Shwachman score | 83.3 | 77.7 | 5.6 | 0.4 to 10.9 | 0.04 |
| No. positive forP aeruginosa | 6 | 11 | 0.12 | ||
| No. ΔF508 homozygous | 17 | 19 | 0.43 |
FEV1 = forced expiratory volume in one second.