Table 1

Some candidate genes for susceptibility to tuberculosis

HLAComplement receptor 1
NRAMP1ICAM 1
Tumour necrosis factorFucosyltransferase 2
Mannose binding proteinInducible nitric oxide synthase
Vitamin D receptorChemokine receptors
Interferon-γ receptorInterleukin 4
Interleukin 10TH2 cluster
Interleukin 1α, 1β and RAInterleukin 6
  • The candidate genes listed all contain known polymorphisms. Many other genes could play a role in tuberculosis susceptibility and are worthy of investigation.