Demographics, questionnaire data and blood gas values
| Normal subjects | Controlled asthma | Uncontrolled asthma | |
| Age (years) | 26.6 (10.8)* | 42.3 (16.6) | 45.6 (17.1) |
| BMI (kg/m2) | 21.1 (2.9)† | 26.6 (2.9) | 27.5 (3.5) |
| Neck circumference (cm) | 34.4 (3.3)‡ | 37.8 (3.2) | 39.2 (4.2) |
| Gender (M:F) | 7:5 | 6:6 | 7:5 |
| Waist/hip ratio | 0.83 (0.06) | 0.89 (0.11) | 0.98 (0.09)§ |
| Epworth Sleepiness Scale (points) | 2.1 (0.9)* | 6.0 (4.2) | 8.6 (4.9) |
| SABAs (n/12) | 0 | 9 | 10 |
| LABAs (n/12) | 0 | 3 | 11 |
| Inhaled corticosteroid (n/12) | 0 | 6 | 12 |
| Pao2 (kPa) | 11.8 (0.4) | 12.0 (1.5) | 10.6 (1.8)§ |
| Paco2 (kPa) | 5.0 (0.2) | 4.9 (0.4) | 5.2 (0.7) |
| pH | 7.40 (0.01) | 7.43 (0.02) | 7.41 (0.02) |
| HCO3− (mmol) | 24.0 (0.4) | 23.7 (1.1) | 24.3 (2.7) |
Comparisons are based on results from ANOVA.
↵* Difference between normal group and controlled asthma (p<0.01).
↵† Difference between normal group and controlled asthma (p<0.001).
↵‡ Difference between normal group and controlled asthma (p<0.05).
↵§ Difference between unccontrolled versus controlled asthma and uncontrolled asthma versus normal group (p<0.05).
BMI, body mass index; F, females; LABAs, long-acting β-agonists; M, males; SABAs, short-acting β-agonists.