Patient characteristics at the start and completion of antibiotic treatment for an exacerbation and when stable
| Start of IV antibiotics | Completion of IV antibiotics | Stable | |||||
| Mean (SD) | Mean (SD) | Mean difference from start* (95% CI) | p Value | Mean (SD) | Mean difference from start* (95% CI) | p Value | |
| (n=26) | (n=26) | (n=13) | |||||
| Weight (kg) | 59.25 (10.70) | 59.09 (10.93) | −0.16 (−0.48 to 0.17) | 0.33 | 59.27 (12.92) | +0.28 (−0.05 to 0.60) | 0.09 |
| FEV1 (l) | 1.65 (0.76) | 2.05 (0.84) | +0.39 (0.21 to 0.58) | <0.001 | 1.71 (0.66) | +0.12 (−0.05 to 0.30) | 0.16 |
| CRP (mg/l)* | 11.7 (3.8–28.8) | 7.4 (3.5–14.5) | −7.6 (−2.0 to −21.5) | 0.005 | 13.0 (2.8–33.5) | +0.5 (−33.5 to 15.8) | 0.91 |
| WCC (×109/l)* | 10.1 (8.1–14.2) | 7.2 (6.0–10.3) | −2.5 (−4.7 to −0.8) | 0.01 | 12.5 (10.2–16.1) | +1.9 (−3.7 to +4.5) | 0.58 |
↵* As CRP and WCC are skewed, the median and IQR are presented along with the median difference from start (95% CI) and the p value from the Wilcoxon signed rank test.
CRP, C reactive protein; FEV1, forced expiratory volume in 1 s; IV, intravenous; WCC, white cell count.