Mean (SE) GM-CSF (ng/ml) and TNFα (pg/ml) concentrations in normal and asthmatic subjects following inhalation of endotoxin or placebo
| Placebo | Endotoxin | ||||||
|---|---|---|---|---|---|---|---|
| Baseline | 6 hours | 24 hours | Baseline | 6 hours | 24 hours | ||
| Normal | |||||||
| GM-CSF | 0.5 (0.1) | 0.5 (0.1) | 0.6 (0.1) | 0.5 (0.1) | 0.5 (0.1) | 0.5 (0.1) | |
| TNFα | 0.0 (0.0) | 49.0 (23.0) | 18.6 (9.7) | 25.1 (16.6) | 56.7 (48.0) | 27.1 (20.4) | |
| Asthma | |||||||
| GM-CSF | 0.6 (0.1) | 0.6 (0.1) | 0.4 (0.05) | 0.5 (0.1) | 0.4 (0.1) | 0.6 (0.1) | |
| TNFα | 84.9 (38.7) | 127.0 (76.6) | 81.6 (36.6) | 112.0 (42.9) | 41.4 (28.2) | 45.5 (21.6) | |