Incidence rates and Poisson regression modelling of idiopathic pulmonary fibrosis clinical syndrome incidence (using the THIN data set)
Cases | Crude incidence rates (95% CI) per 100 000 person-years | Rate ratios (95% CI) | |
Year | |||
2000 | 160 | 5.77 (4.95 to 6.74) | 1.0 |
2001 | 179 | 6.12 (5.28 to 7.08) | 1.08 (0.87 to 1.33) |
2002 | 203 | 6.69 (5.83 to 7.68) | 1.20 (0.98 to 1.48) |
2003 | 221 | 7.14 (6.26 to 8.15) | 1.30 (1.06 to 1.60) |
2004 | 253 | 8.08 (7.14 to 9.14) | 1.41 (1.16 to 1.72) |
2005 | 260 | 8.14 (7.21 to 9.19) | 1.45 (1.19 to 1.77) |
2006 | 243 | 7.54 (6.65 to 8.55) | 1.35 (1.11 to 1.65) |
2007 | 294 | 9.05 (8.07 to 10.15) | 1.63 (1.34 to 1.98) |
2008 | 261 | 8.04 (7.12 to 9.08) | 1.37 (1.12 to 1.67) p for trend <0.0001 |
Sex | |||
Male | 1307 | 9.46 (8.96 to 9.98) | 1.0 |
Female | 767 | 5.46 (5.07 to 5.86) | 0.44 (0.40 to 0.48) p<0.0001 |
Age group (years) | |||
≤54 | 187 | 0.86 (0.75 to 1.00) | 0.02 (0.02 to 0.03) |
55–59 | 180 | 10.48 (9.06 to 12.13) | 0.28 (0.23 to 0.33) |
60–64 | 250 | 20.76 (18.34 to 23.50) | 0.56 (0.47 to 0.65) |
65–69 | 386 | 36.45 (32.99 to 40.27) | 1.0 |
70–74 | 425 | 47.57 (43.26 to 52.32) | 1.35 (1.18 to 1.55) |
75–79 | 365 | 47.38 (42.76 to 52.49) | 1.359 (1.21 to 1.61) |
80–84 | 211 | 60.05 (52.47 to 68.73) | 1.89 (1.59 to 2.23) |
≥85 | 70 | 34.82 (27.55 to 44.01) | 1.18 (0.92 to 1.53) p for trend <0.0001 |
Health authority | |||
East Midlands | 84 | 6.85 (5.53 to 8.48) | 1.27 (0.98 to 1.66) |
East of England | 150 | 6.46 (5.50 to 7.58) | 1.13 (0.90 to 1.42) |
London | 170 | 5.81 (5.00 to 6.76) | 1.30 (1.04 to 1.62) |
North East | 80 | 8.22 (6.60 to 10.23) | 1.46 (1.11 to 1.91) |
North West | 276 | 10.14 (9.01 to 11.41) | 1.91 (1.57 to 2.33) |
Northern Ireland | 82 | 7.48 (6.02 to 9.28) | 1.64 (1.25 to 2.15) |
Scotland | 171 | 8.12 (6.99 to 9.44) | 1.53 (1.25 to 1.91) |
South Central | 221 | 6.88 (6.03 to 7.84) | 1.18 (0.96 to 1.46) |
South East Coast | 151 | 5.74 (4.89 to 6.73) | 1.0 |
South West | 255 | 8.70 (7.69 to 9.84) | 1.37 (1.11 to 1.67) |
Wales | 135 | 8.22 (6.95 to 9.73) | 1.46 (1.16 to 1.85) |
West Midlands | 195 | 7.12 (6.19 to 8.19) | 1.31 (1.06 to 1.62) |
Yorkshire and Humber | 104 | 7.73 (6.38 to 9.37) | 1.34 (1.05 to 1.73) p<0.0001 |
All the incidence rate ratios are mutually adjusted for all other variables in the table.
THIN, The Health Improvement Network.