Standardised mortality rates and Poisson regression modelling of deaths from idiopathic pulmonary fibrosis clinical syndrome (using the ONS data set)
No. of deaths | Person-years (million) | Mortality rates standardised to 2008 population per 100 000 person-years (95% CI) | Mutually adjusted rate ratios (95% CI) | |
Calendar period | ||||
ICD-8 | ||||
1968–1972 | 2509 | 270 | 0.92 (0.87 to 0.96) | 1.0 |
1973–1978 | 3498 | 330 | 1.07 (1.04 to 1.11) | 1.17 (1.10 to 1.22) |
1979–1983 | 3858 | 270 | 1.42 (1.37 to 1.46) | 1.54 (1.46 to 1.62) |
ICD-9 | ||||
1984–1988 | 5888 | 270 | 2.16 (2.11 to 2.22) | 2.35 (2.24 to 2.46) |
1989–1994 | 8652 | 330 | 2.65 (2.60 to 2.71) | 2.87 (2.75 to 3.00) |
1995–2000 | 11580 | 330 | 3.55 (3.48 to 3.61) | 3.85 (3.68 to 4.01) |
ICD-10 | ||||
2001–2004 | 9589 | 220 | 4.40 (4.32 to 4.49) | 4.78 (4.57 to 4.99) |
2005–2008 | 11101 | 220 | 5.10 (5.00 to 5.19) | 5.53 (5.30 to 5.78) p for trend <0.0001 |
Sex | ||||
Male | 34639 | 1000 | 3.16 (3.12 to 3.19) | 1.0 |
Female | 22036 | 1100 | 1.94 (1.92 to 1.97) | 0.49 (0.48 to 0.49) p<0.0001 |
Age group (years) | ||||
≤54 | 2622 | 1600 | 0.16 (0.16 to 0.17) | 0.02 (0.02 to 0.02) |
55–59 | 2504 | 130 | 1.90 (1.83 to 1.98) | 0.26 (0.25 to 0.27) |
60–64 | 4410 | 130 | 3.33 (3.23 to 3.42) | 0.46 (0.44 to 0.47) |
65–69 | 7240 | 100 | 7.25 (7.09 to 7.42) | 1.0 |
70–74 | 10013 | 87 | 11.51 (11.29 to 11.74) | 1.60 (1.55 to 1.65) |
75–79 | 11524 | 72 | 15.95 (15.66 to 16.24) | 2.26 (2.20 to 2.33) |
80–84 | 10088 | 53 | 18.93 (18.56 to 19.30) | 2.77 (2.68 to 2.85) |
≥85 | 8274 | 49 | 16.72 (16.36 to 17.09) | 2.60 (2.52 to 2.69) p for trend <0.0001 |
All the mortality rate ratios are mutually adjusted for all other variables in the table.
ICD, International Classification of Diseases; ONS, Office for National Statistics.