TY - JOUR T1 - Getting innovative bronchoscopic techniques into real clinical practice JF - Thorax JO - Thorax SP - 327 LP - 328 DO - 10.1136/thoraxjnl-2021-217745 VL - 77 IS - 4 AU - Christophe Dooms AU - Jonas Yserbyt Y1 - 2022/04/01 UR - http://thorax.bmj.com/content/77/4/327.abstract N2 - Advanced flexible bronchoscopy techniques in its current form mainly target for pulmonary nodules >20 mm. These advanced bronchoscopy techniques consist of (ultra)thin bronchoscopes with or without virtual planning for navigation and radial EBUS miniprobes for real-time target verification.1 2 This has led to improved detection capabilities and diagnostic ability for peripheral pulmonary nodule(s) in daily clinical practice compared with classical flexible bronchoscopy. Detection rates around 85% and a diagnostic yields 70%–75% have been reported for pulmonary nodules >20 mm within experienced interventional pulmonology centres.More recently, innovative bronchoscopy techniques leverage current advanced techniques for peripheral pulmonary nodules as small as 15–20 mm. In prospective studies, bronchoscopy guided by cone beam CT and augmented fluoroscopy or robot-assisted bronchoscopy techniques improved the access to target lesions with tool-in-lesion navigation reporting success rates from 90% to 97%.3–6 A diagnostic yield (considering inflammation as non-diagnostic) ranging from 52% to 78% has been reported in these studies with high cancer probability. The discordance between a high tool-in-lesion navigation success rate and a moderate diagnostic yield remains a matter of … ER -