RT Journal Article
SR Electronic
T1 Burden of nosocomial COVID-19 in Wales: results from a multicentre retrospective observational study of 2508 hospitalised adults
JF Thorax
JO Thorax
FD BMJ Publishing Group Ltd and British Thoracic Society
SP 1246
OP 1249
DO 10.1136/thoraxjnl-2021-216964
VO 76
IS 12
A1 Mark J Ponsford
A1 Rhys Jefferies
A1 Chris Davies
A1 Daniel Farewell
A1 Ian R Humphreys
A1 Stephen Jolles
A1 Sara Fairbairn
A1 Keir Lewis
A1 Daniel Menzies
A1 Amit Benjamin
A1 Favas Thaivalappil
A1 Chris Williams
A1 Simon M Barry
YR 2021
UL http://thorax.bmj.com/content/76/12/1246.abstract
AB The burden of nosocomial SARS-CoV-2 infection remains poorly defined. We report on the outcomes of 2508 adults with molecularly-confirmed SARS-CoV-2 admitted across 18 major hospitals, representing over 60% of those hospitalised across Wales between 1 March and 1 July 2020. Inpatient mortality for nosocomial infection ranged from 38% to 42%, consistently higher than participants with community-acquired infection (31%–35%) across a range of case definitions. Those with hospital-acquired infection were older and frailer than those infected within the community. Nosocomial diagnosis occurred a median of 30 days following admission (IQR 21–63), suggesting a window for prophylactic or postexposure interventions, alongside enhanced infection control measures.