RT Journal Article
SR Electronic
T1 Temperature variability and asthma hospitalisation in Brazil, 2000–2015: a nationwide case-crossover study
JF Thorax
JO Thorax
FD BMJ Publishing Group Ltd and British Thoracic Society
SP 962
OP 969
DO 10.1136/thoraxjnl-2020-216549
VO 76
IS 10
A1 Wu, Yao
A1 Xu, Rongbin
A1 Wen, Bo
A1 Coelho, Micheline de Sousa Zanotti Stagliorio
A1 Saldiva, Paulo H
A1 Li, Shanshan
A1 Guo, Yuming
YR 2021
UL http://thorax.bmj.com/content/76/10/962.abstract
AB Background Both cold and hot temperature have been associated with the onset of asthma, but it remains largely unknown about the risk of asthma hospitalisation associated with short-term temperature fluctuation or temperature variability (TV).Objective To explore the association between short-term exposure to TV and asthma hospitalisation in Brazil.Methods Data for asthma hospitalisation and weather conditions were collected from 1816 Brazilian cities between 2000 and 2015. TV was calculated as the SD of all daily minimum and maximum temperatures within 0–7 days prior to current day. A time-stratified case-crossover design was performed to quantify the association between TV and hospitalisation for asthma.Results A total of 2 818 911 hospitalisations for asthma were identified during the study period. Each 1°C increase in 0–7 days’ TV exposure was related to a 1.0% (95% CI 0.7% to 1.4%) increase in asthma hospitalisations. The elderly were more vulnerable to TV than other age groups, while region and season appeared to significantly modify the associations. There were 159 305 (95% CI 55 293 to 2 58 054) hospitalisations, US$48.41 million (95% CI US$16.92 to US$78.30 million) inpatient costs at 2015 price and 450.44 thousand inpatient days (95% CI 156.08 to 729.91 thousand days) associated with TV during the study period. The fraction of asthma hospitalisations attributable to TV increased from 5.32% in 2000 to 5.88% in 2015.Conclusion TV was significantly associated with asthma hospitalisation and the corresponding substantial health costs in Brazil. Our findings suggest that preventive measures of asthma should take TV into account.No data are available.