RT Journal Article
SR Electronic
T1 Impact of chronic use of heat-not-burn cigarettes on oxidative stress, endothelial dysfunction and platelet activation: the SUR-VAPES Chronic Study
JF Thorax
JO Thorax
FD BMJ Publishing Group Ltd and British Thoracic Society
SP 618
OP 620
DO 10.1136/thoraxjnl-2020-215900
VO 76
IS 6
A1 Lorenzo Loffredo
A1 Roberto Carnevale
A1 Simona Battaglia
A1 Roberta Marti
A1 Stefano Pizzolo
A1 Simona Bartimoccia
A1 Cristina Nocella
A1 Vittoria Cammisotto
A1 Sebastiano Sciarretta
A1 Isotta Chimenti
A1 Elena De Falco
A1 Elena Cavarretta
A1 Mariangela Peruzzi
A1 Antonino Marullo
A1 Fabio Miraldi
A1 Francesco Violi
A1 Andrea Morelli
A1 Giuseppe Biondi-Zoccai
A1 Giacomo Frati
YR 2021
UL http://thorax.bmj.com/content/76/6/618.abstract
AB Tobacco habit still represents the leading preventable cause of morbidity and mortality worldwide. Heat-not-burn cigarettes (HNBCs) are considered as an alternative to traditional combustion cigarettes (TCCs) due to the lack of combustion and the absence of combustion-related specific toxicants. The aim of this observational study was to assess the effect of HNBC on endothelial function, oxidative stress and platelet activation in chronic adult TCC smokers and HNBC users. The results showed that both HNBC and TCC display an adverse phenotype in terms of endothelial function, oxidative stress and platelet activation. Future randomised studies are strongly warranted to confirm these data.