RT Journal Article
SR Electronic
T1 Associations of CT evaluations of antigravity muscles, emphysema and airway disease with longitudinal outcomes in patients with COPD
JF Thorax
JO Thorax
FD BMJ Publishing Group Ltd and British Thoracic Society
SP 295
OP 297
DO 10.1136/thoraxjnl-2020-215085
VO 76
IS 3
A1 Naoya Tanabe
A1 Susumu Sato
A1 Kazuya Tanimura
A1 Tsuyoshi Oguma
A1 Atsuyasu Sato
A1 Shigeo Muro
A1 Toyohiro Hirai
YR 2021
UL http://thorax.bmj.com/content/76/3/295.abstract
AB Multiple CT indices are associated with disease progression and mortality in patients with COPD, but which indices have the strongest association remain unestablished. This longitudinal 10-year observational study (n=247) showed that the emphysema severity on CT is more closely associated with the progression of airflow limitation and that a reduction in the cross-sectional area of erector spinae muscles (ESMCSA) on CT is more closely associated with mortality than the other CT indices, independent of patient demographics and pulmonary function. ESMCSA is a useful CT index that is more closely associated with long-term mortality than emphysema and airway disease in patients with COPD.