PT  - JOURNAL ARTICLE
AU  - Naoya Tanabe
AU  - Susumu Sato
AU  - Kazuya Tanimura
AU  - Tsuyoshi Oguma
AU  - Atsuyasu Sato
AU  - Shigeo Muro
AU  - Toyohiro Hirai
TI  - Associations of CT evaluations of antigravity muscles, emphysema and airway disease with longitudinal outcomes in patients with COPD
AID  - 10.1136/thoraxjnl-2020-215085
DP  - 2021 Mar 01
TA  - Thorax
PG  - 295--297
VI  - 76
IP  - 3
4099  - http://thorax.bmj.com/content/76/3/295.short
4100  - http://thorax.bmj.com/content/76/3/295.full
SO  - Thorax2021 Mar 01; 76
AB  - Multiple CT indices are associated with disease progression and mortality in patients with COPD, but which indices have the strongest association remain unestablished. This longitudinal 10-year observational study (n=247) showed that the emphysema severity on CT is more closely associated with the progression of airflow limitation and that a reduction in the cross-sectional area of erector spinae muscles (ESMCSA) on CT is more closely associated with mortality than the other CT indices, independent of patient demographics and pulmonary function. ESMCSA is a useful CT index that is more closely associated with long-term mortality than emphysema and airway disease in patients with COPD.