TY - JOUR T1 - Modification of a domiciliary ventilator to increase FiO<sub>2</sub>: an off-label modification which may be of value in COVID-19 JF - Thorax JO - Thorax SP - 83 LP - 85 DO - 10.1136/thoraxjnl-2020-215487 VL - 76 IS - 1 AU - Yoseph Mebrate AU - Steven Phillips AU - Debbie Field AU - Ivy Mumuni AU - Paul Josse AU - David Alexander AU - Rishi Das-Gupta AU - Richard Trimlett AU - Michael I Polkey Y1 - 2021/01/01 UR - http://thorax.bmj.com/content/76/1/83.abstract N2 - Although nasal continuous positive airway pressure or non-invasive ventilation is used to manage some patients with acute lung injury due to COVID-19, such patients also demonstrate increased minute ventilation which makes it hard, if the device is used in line with the manufacturer’s instructions, to achieve adequate oxygen delivery. In addition, if a hospital contains many such patients, then it is possible that the oxygen requirements will exceed infrastructure capacity. Here we describe a simple modification of two exemplar ventilators normally used for domiciliary ventilation, which substantially increased the fraction of inspired oxygen (FiO2) delivered. ER -