TY - JOUR T1 - Histopathological findings in fatal COVID-19 severe acute respiratory syndrome: preliminary experience from a series of 10 Spanish patients JF - Thorax JO - Thorax SP - 1116 LP - 1118 DO - 10.1136/thoraxjnl-2020-215577 VL - 75 IS - 12 AU - Borja Recalde-Zamacona AU - Laura García-Tobar AU - Alan Argueta AU - Laura Álvarez AU - Carlos Eduardo De Andrea AU - Mirian Fernández Alonso AU - Ana Ezponda AU - Francisco Carmona Torre AU - Carlota Jordán Iborra AU - Jorge Augusto Quiroga AU - Jose Luis Del Pozo AU - Javier J Zulueta AU - Gema Echarri AU - Manuel F Landecho AU - Maria Dolores Lozano Y1 - 2020/12/01 UR - http://thorax.bmj.com/content/75/12/1116.abstract N2 - In December 2019, an outbreak of severe acute respiratory syndrome associated to SARS-CoV2 was reported in Wuhan, China. To date, little is known on histopathological findings in patients infected with the new SARS-CoV2. Lung histopathology shows features of acute and organising diffuse alveolar damage. Subtle cellular inflammatory infiltrate has been found in line with the cytokine storm theory. Medium-size vessel thrombi were frequent, but capillary thrombi were not present. Despite the elevation of biochemical markers of cardiac injury, little histopathological damage could be confirmed. Viral RNA from paraffin sections was detected at least in one organ in 90% patients. ER -