@article {Cunningham172, author = {Steve Cunningham and Catriona Graham and Morag MacLean and Paul Aurora and Michael Ashworth and Angelo Barbato and Alistair Calder and Julia Carlens and Annick Clement and Meike Hengst and Birgit Kammer and Nural Kiper and Katarzyna Krenke and Kai Kronfeld and Joanna Lange and Julia Ley-Zaporozhan and Andrew G Nicholson and Simone Reu and Traudl Wesselak and Martin Wetzke and Andrew Bush and Nicolaus Schwerk and Matthias Griese}, editor = {, and , and Bhatt, Jayesh and Buchvald, Frederik and Cobanoglu, Nazan and Child, Fran and Chinedu, Nwokoro and Donato, Leonard and Epaud, Ralph and Escribano, Ampara and Freihorst, Achim and Gupta, Atul and Guy, Emma and H{\"u}bner, Tobias and Kind-Jugend, Petra Kaiser-Labusch and Lex, Christiane and Mayell, Sarah and Moss, Samantha and Emiralioglu, Nagehan and N{\"a}hrlich, Lutz and Nathan, Nadia and O{\textquoteright}Reilly, Ruth and Regamey, Nicolas and Rochat, Isabelle and Rosewich, Martin and Sismanlar, Tugbu and Snijders, Deborah and Stehling, Florian}, title = {One-year outcomes in a multicentre cohort study of incident rare diffuse parenchymal lung disease in children (ChILD)}, volume = {75}, number = {2}, pages = {172--175}, year = {2020}, doi = {10.1136/thoraxjnl-2019-213217}, publisher = {BMJ Publishing Group Ltd}, abstract = {We performed a prospective, observational, cohort study of children newly diagnosed with children{\textquoteright}s interstitial lung disease (ChILD), with structured follow-up at 4, 8, 12 weeks and 6 and 12 months. 127 children, median age 0.9 (IQR 0.3{\textendash}7.9) years had dyspnoea (68\%, 69/102), tachypnoea (75\%, 77/103) and low oxygen saturation (SpO2) median 92\% (IQR 88{\textendash}96). Death (n=20, 16\%) was the most common in those \<6 months of age with SpO2\<94\% and developmental/surfactant disorders. We report for the first time that ChILD survivors improved multiple clinical parameters within 8{\textendash}12 weeks of diagnosis. These data can inform family discussions and support clinical trial measurements.}, issn = {0040-6376}, URL = {https://thorax.bmj.com/content/75/2/172}, eprint = {https://thorax.bmj.com/content/75/2/172.full.pdf}, journal = {Thorax} }