TY - JOUR T1 - <em>Burkholderia cenocepacia</em> ET12 transmission in adults with cystic fibrosis JF - Thorax JO - Thorax SP - 88 LP - 90 DO - 10.1136/thoraxjnl-2019-214098 VL - 75 IS - 1 AU - Ana C Blanchard AU - Lin Tang AU - Manal Tadros AU - Matthew Muller AU - Theodore Spilker AU - Valerie J Waters AU - John J LiPuma AU - Elizabeth Tullis Y1 - 2020/01/01 UR - http://thorax.bmj.com/content/75/1/88.abstract N2 - This report describes transmission of a Burkholderia cenocepacia ET12 strain (ET12-Bc) at the Toronto Adult Cystic Fibrosis (CF) Centre occurring from 2008 to 2017. Epidemiological and genomic data from 11 patients with CF were evaluated. Isolates were analysed using whole genome sequencing (WGS). Epidemiological investigation and WGS analysis suggested nosocomial transmission, despite enhanced infection control precautions. This was associated with subsequent deaths in 10 patients. ET12-Bc positive patients are no longer cared for on the same unit as ET12-Bc negative patients. ER -