PT  - JOURNAL ARTICLE
AU  - Ana C Blanchard
AU  - Lin Tang
AU  - Manal Tadros
AU  - Matthew Muller
AU  - Theodore Spilker
AU  - Valerie J Waters
AU  - John J LiPuma
AU  - Elizabeth Tullis
TI  - <em>Burkholderia cenocepacia</em> ET12 transmission in adults with cystic fibrosis
AID  - 10.1136/thoraxjnl-2019-214098
DP  - 2020 Jan 01
TA  - Thorax
PG  - 88--90
VI  - 75
IP  - 1
4099  - http://thorax.bmj.com/content/75/1/88.short
4100  - http://thorax.bmj.com/content/75/1/88.full
SO  - Thorax2020 Jan 01; 75
AB  - This report describes transmission of a Burkholderia cenocepacia ET12 strain (ET12-Bc) at the Toronto Adult Cystic Fibrosis (CF) Centre occurring from 2008 to 2017. Epidemiological and genomic data from 11 patients with CF were evaluated. Isolates were analysed using whole genome sequencing (WGS). Epidemiological investigation and WGS analysis suggested nosocomial transmission, despite enhanced infection control precautions. This was associated with subsequent deaths in 10 patients. ET12-Bc positive patients are no longer cared for on the same unit as ET12-Bc negative patients.