PT - JOURNAL ARTICLE AU - Crosbie, Phil A AU - Balata, Haval AU - Evison, Matthew AU - Atack, Melanie AU - Bayliss-Brideaux, Val AU - Colligan, Denis AU - Duerden, Rebecca AU - Eaglesfield, Josephine AU - Edwards, Timothy AU - Elton, Peter AU - Foster, Julie AU - Greaves, Melanie AU - Hayler, Graham AU - Higgins, Coral AU - Howells, John AU - Irion, Klaus AU - Karunaratne, Devinda AU - Kelly, Jodie AU - King, Zoe AU - Lyons, Judith AU - Manson, Sarah AU - Mellor, Stuart AU - Miller, Donna AU - Myerscough, Amanda AU - Newton, Tom AU - O’Leary, Michelle AU - Pearson, Rachel AU - Pickford, Julie AU - Sawyer, Richard AU - Screaton, Nick J AU - Sharman, Anna AU - Simmons, Maggi AU - Smith, Elaine AU - Taylor, Ben AU - Taylor, Sarah AU - Walsham, Anna AU - Watts, Angela AU - Whittaker, James AU - Yarnell, Laura AU - Threlfall, Anthony AU - Barber, Phil V AU - Tonge, Janet AU - Booton, Richard TI - Second round results from the Manchester ‘Lung Health Check’ community-based targeted lung cancer screening pilot AID - 10.1136/thoraxjnl-2018-212547 DP - 2019 Jul 01 TA - Thorax PG - 700--704 VI - 74 IP - 7 4099 - http://thorax.bmj.com/content/74/7/700.short 4100 - http://thorax.bmj.com/content/74/7/700.full SO - Thorax2019 Jul 01; 74 AB - We report results from the second annual screening round (T1) of Manchester’s ‘Lung Health Check’ pilot of community-based lung cancer screening in deprived areas (undertaken June to August 2017). Screening adherence was 90% (n=1194/1323): 92% of CT scans were classified negative, 6% indeterminate and 2.5% positive; there were no interval cancers. Lung cancer incidence was 1.6% (n=19), 79% stage I, treatments included surgery (42%, n=9), stereotactic ablative radiotherapy (26%, n=5) and radical radiotherapy (5%, n=1). False-positive rate was 34.5% (n=10/29), representing 0.8% of T1 participants (n=10/1194). Targeted community-based lung cancer screening promotes high screening adherence and detects high rates of early stage lung cancer.