RT Journal Article
SR Electronic
T1 Diabetes mellitus and latent tuberculosis infection: baseline analysis of a large UK cohort
JF Thorax
JO Thorax
FD BMJ Publishing Group Ltd and British Thoracic Society
SP 91
OP 94
DO 10.1136/thoraxjnl-2017-211124
VO 74
IS 1
A1 Charlotte Jackson
A1 Jo Southern
A1 Ajit Lalvani
A1 Francis Drobniewski
A1 Chris J Griffiths
A1 Marc Lipman
A1 Graham H Bothamley
A1 Jonathan J Deeks
A1 Ambreen Imran
A1 Onn Min Kon
A1 Sithembinkosi Mpofu
A1 Vladyslav Nikolayevskyy
A1 Melanie Rees-Roberts
A1 Alice Sitch
A1 Saranya Sridhar
A1 Chuen-Yan Tsou
A1 Hilary Whitworth
A1 Ibrahim Abubakar
YR 2019
UL http://thorax.bmj.com/content/74/1/91.abstract
AB We conducted a cross-sectional analysis of baseline data from a UK cohort study which enrolled participants at risk of latent tuberculosis infection (LTBI, defined as a positive result for either of the two interferon gamma release assays). Binomial regression with a log link was used to estimate crude and adjusted prevalence ratios (PRs) and 95% CIs for the relationship between diabetes mellitus (DM) and LTBI. Adjusted for age, sex, ethnicity, body mass index and the presence of other immunocompromising conditions, DM was associated with a 15% higher prevalence of LTBI (adjusted PR=1.15, 95% CI 1.02 to 1.30, p=0.025).Trial registration number PREDICT is registered on clinicaltrials.gov (NCT01162265)