RT Journal Article SR Electronic T1 Do guidelines for treating chest disease in children use Cochrane Reviews effectively? A systematic review JF Thorax JO Thorax FD BMJ Publishing Group Ltd and British Thoracic Society SP 670 OP 673 DO 10.1136/thoraxjnl-2016-208790 VO 73 IS 7 A1 Andrew P Prayle A1 Tessy Cox A1 Sherie J Smith A1 Joanne Rycroft-Malone A1 Kim S Thomas A1 Dyfrig A Hughes A1 Alan R Smyth YR 2018 UL http://thorax.bmj.com/content/73/7/670.abstract AB Cochrane Reviews summarise best evidence and should inform guidelines. We assessed the use of Cochrane Reviews in the UK guidelines for paediatric respiratory disease. We found 21 guidelines which made 1025 recommendations, of which 96 could be informed by a Cochrane Review. In 38/96 recommendations (40%), some or all of the relevant Cochrane Reviews were not cited. We linked recommendations to 140 Cochrane Reviews. In 37/140 (26%) cases, the guideline recommendation did not fully agree with the Cochrane Review. Guideline developers may fail to use Cochrane Reviews or may make recommendations which are not in line with best evidence.