%0 Journal Article %A Charlotte Jackson %A Jo Southern %A Ajit Lalvani %A Francis Drobniewski %A Chris J Griffiths %A Marc Lipman %A Graham H Bothamley %A Jonathan J Deeks %A Ambreen Imran %A Onn Min Kon %A Sithembinkosi Mpofu %A Vladyslav Nikolayevskyy %A Melanie Rees-Roberts %A Alice Sitch %A Saranya Sridhar %A Chuen-Yan Tsou %A Hilary Whitworth %A Ibrahim Abubakar %T Diabetes mellitus and latent tuberculosis infection: baseline analysis of a large UK cohort %D 2018 %R 10.1136/thoraxjnl-2017-211124 %J Thorax %P thoraxjnl-2017-211124 %X We conducted a cross-sectional analysis of baseline data from a UK cohort study which enrolled participants at risk of latent tuberculosis infection (LTBI, defined as a positive result for either of the two interferon gamma release assays). Binomial regression with a log link was used to estimate crude and adjusted prevalence ratios (PRs) and 95% CIs for the relationship between diabetes mellitus (DM) and LTBI. Adjusted for age, sex, ethnicity, body mass index and the presence of other immunocompromising conditions, DM was associated with a 15% higher prevalence of LTBI (adjusted PR=1.15, 95% CI 1.02 to 1.30, p=0.025).Trial registration number PREDICT is registered on clinicaltrials.gov (NCT01162265) %U https://thorax.bmj.com/content/thoraxjnl/early/2018/05/15/thoraxjnl-2017-211124.full.pdf