RT Journal Article
SR Electronic
T1 Influence of muscle mass in the assessment of lower limb strength in COPD: validation of the prediction equation
JF Thorax
JO Thorax
FD BMJ Publishing Group Ltd and British Thoracic Society
SP 587
OP 589
DO 10.1136/thoraxjnl-2016-209870
VO 73
IS 6
A1 Trethewey, Ruth
A1 Esliger, Dale
A1 Petherick, Emily
A1 Evans, Rachael
A1 Greening, Neil
A1 James, Benjamin
A1 Kingsnorth, Andrew
A1 Morgan, Mike
A1 Orme, Mark
A1 Sherar, Lauren
A1 Singh, Sally
A1 Toms, Nicole
A1 Steiner, Michael
YR 2018
UL http://thorax.bmj.com/content/73/6/587.abstract
AB Absence of established reference values limits application of quadriceps maximal voluntary contraction (QMVC) measurement. The impact of muscle mass inclusion in predictions is unclear. Prediction equations encompassing gender, age and size with (FFM+) and without (FFM−), derived in healthy adults (n=175), are presented and compared in two COPD cohorts recruited from primary care (COPD-PC, n=112) and a complex care COPD clinic (COPD-CC, n=189). Explained variance was comparable between the prediction models (R2: FFM+: 0.59, FFM−: 0.60) as were per cent predictions in COPD-PC (88.8%, 88.3%). However, fat-free mass inclusion reduced the prevalence of weakness in COPD, particularly in COPD-CC where 11.9% fewer were deemed weak.