TY - JOUR T1 - Aortic rupture involving matrix metalloproteinases 8 and 9 during <em>Staphylococcus aureus</em> pneumonia JF - Thorax JO - Thorax SP - 397 LP - 398 DO - 10.1136/thoraxjnl-2017-210784 VL - 73 IS - 4 AU - Mitsuo Hashimoto AU - Saki Kuriiwa AU - Ayako Kojima AU - Shunsuke Minagawa AU - Takanori Numata AU - Hiromichi Hara AU - Jun Araya AU - Yumi Kaneko AU - Katsutoshi Nakayama AU - Mamiko Owada AU - Daisuke Aizawa AU - Takashi Yorozu AU - Masafumi Suzuki AU - Kazuyoshi Kuwano Y1 - 2018/04/01 UR - http://thorax.bmj.com/content/73/4/397.abstract N2 - An 87-year-old man was admitted to Jikei University Hospital presenting with fever and fatigue. Physical examinations revealed inspiratory coarse crackles on the left lung field. A chest CT detected a tumour-like consolidation around the thoracic aorta (figure 1A). Biochemical examinations found a high number of white blood cells and elevated C-reactive protein level, and a diagnosis of pneumonia was made. Penicillin antibiotics (ampicillin/sulbactam) were administered. Two days later, methicillin-sensitive Staphylococcus aureus (MSSA) was detected in two sets of blood cultures. An echocardiogram showed no vegetation and a urine culture was negative. A sputum culture was unobtainable, but pneumonia was the only focus of infection for the MSSA. Penicillin antibiotics were continued, but the patient suddenly developed cardiopulmonary arrest … ER -