PT - JOURNAL ARTICLE ED - , TI - S93 Effect of lumacaftor/ivacaftor on total, bronchiectasis, and air trapping computed tomography (ct) scores in children homozygous for f508del-cftr: exploratory imaging substudy AID - 10.1136/thoraxjnl-2017-210983.458 DP - 2017 Dec 01 TA - Thorax PG - A257--A257 VI - 72 IP - Suppl 3 4099 - http://thorax.bmj.com/content/72/Suppl_3/A257.2.short 4100 - http://thorax.bmj.com/content/72/Suppl_3/A257.2.full SO - Thorax2017 Dec 01; 72 AB - AS Brody reports personal fees from Vertex Pharmaceuticals during the conduct of the study.S Nagle reports personal consulting fees from Vertex Pharmaceuticals during the conduct of the study; non-financial support from GE Healthcare (institution/department support).C Hug, G Marigowda, D Waltz, L Wang are employees of Vertex Pharmaceuticals and may hold stock and/or stock options in the company.J Goldin reports ‘other’ conflicts – Founder of MedQIA during the conduct of the study.F Ratjen reports grants and personal fees from Vertex Pharmaceuticals, personal consulting fees from Novartis, Bayer, Roche, Genetech, and Prosteostasis.