RT Journal Article SR Electronic T1 Chronic breathlessness associated with poorer physical and mental health-related quality of life (SF-12) across all adult age groups JF Thorax JO Thorax FD BMJ Publishing Group Ltd and British Thoracic Society SP 1151 OP 1153 DO 10.1136/thoraxjnl-2016-209908 VO 72 IS 12 A1 Currow, D C A1 Dal Grande, E A1 Ferreira, D A1 Johnson, M J A1 McCaffrey, N A1 Ekström, M YR 2017 UL http://thorax.bmj.com/content/72/12/1151.abstract AB Little is known about the impact of chronic breathlessness (modified Medical Research Council (mMRC) score ≥2 for most days, at least three of the last six months) on health-related quality of life (Short Form-12 (SF-12)). 3005 adults from randomly selected households were interviewed face-to-face in South Australia. mMRC ≥2 community prevalence was 2.9%. Adjusted analyses showed clinically meaningful and statistically significant decrements of physical and mental components of SF-12 (mean SF-12 summary scores in physical (−13.0 (−16.0 to −10.2)) and mental (−10.7 (−13.7 to −7.8)) components compared with people with mMRC=0) as chronic breathlessness severity increased, across five age groupings.