PT - JOURNAL ARTICLE AU - D C Currow AU - E Dal Grande AU - D Ferreira AU - M J Johnson AU - N McCaffrey AU - M Ekström TI - Chronic breathlessness associated with poorer physical and mental health-related quality of life (SF-12) across all adult age groups AID - 10.1136/thoraxjnl-2016-209908 DP - 2017 Dec 01 TA - Thorax PG - 1151--1153 VI - 72 IP - 12 4099 - http://thorax.bmj.com/content/72/12/1151.short 4100 - http://thorax.bmj.com/content/72/12/1151.full SO - Thorax2017 Dec 01; 72 AB - Little is known about the impact of chronic breathlessness (modified Medical Research Council (mMRC) score ≥2 for most days, at least three of the last six months) on health-related quality of life (Short Form-12 (SF-12)). 3005 adults from randomly selected households were interviewed face-to-face in South Australia. mMRC ≥2 community prevalence was 2.9%. Adjusted analyses showed clinically meaningful and statistically significant decrements of physical and mental components of SF-12 (mean SF-12 summary scores in physical (−13.0 (−16.0 to −10.2)) and mental (−10.7 (−13.7 to −7.8)) components compared with people with mMRC=0) as chronic breathlessness severity increased, across five age groupings.