TY - JOUR T1 - Macroscopic inflammatory tracheal and endobronchial nodules in Sjögren's syndrome JF - Thorax JO - Thorax SP - 864 LP - 865 DO - 10.1136/thoraxjnl-2016-209390 VL - 72 IS - 9 AU - Hiromichi Hara AU - Kazuyoshi Kuwano AU - Shunsuke Minagawa AU - Takanori Numata AU - Jun Araya AU - Katsutoshi Nakayama Y1 - 2017/09/01 UR - http://thorax.bmj.com/content/72/9/864.abstract N2 - A 38-year-old woman with primary Sjögren's syndrome (SS) presented with a 1 month history of cough and chest pain. She had been treated with prednisolone for organising pneumonia and had been on prednisolone (5 mg/day). Flexible bronchoscopy revealed macroscopic multiple nodules mainly in trachea and in both main bronchus (figure 1A). Three-dimensional CT (3D-CT) also demonstrated multiple nodules in the same place (figure 1B). Endobronchial biopsy showed polyclonal lymphocyte infiltration in the bronchial submucosa and epithelium in part (figure 1C, H & E: upper, CD3: middle, CD20: lower). There were few IgG4-positive plasma cells in the lesion. Amyloid … ER -